A Brief Review of Verbesina crocata (Cav.) Less., a Scantly Studied Medicinal Plant

Document Type : Review

Authors

Department of Biological Systems, Metropolitan Autonomous University Campus Xochimilco, Mexico City, Mexico.

Abstract

Although Verbesina crocata (Cav.) Less. is commonly used in Mexico as a medicinal plant to treat numerous disorders (a tradition dating back to pre-Hispanic times), scant scientific evidence exists on its pharmacological activity. The current review compiles information on the botanical characteristics, traditional medicinal use, and scientific evidence of the pharmacological effects of V. crocata with the aim of orienting future research. This narrative review searched for information on V. crocata with the key words “Verbesina crocata” and its local name “Capitaneja” from the following databases: PubMed, Scopus, EBSCO, SciELO, ScienceDirect, and Google Scholar. Few studies were found about the therapeutic effects of V. crocata in experimental animal models. Empirical knowledge of the effects of preparations predominated over scientific evidence. Among the diverse medicinal applications of V. crocata in Mexico, only its wound healing, antidiabetic, and diuretic activity have been tested scientifically. Little is known about the active constituents of the plant and less about their mechanisms of action or toxicity. Terpenes/steroids, glycosides, alkaloids, coumarins, quinones, saponins, and tannins have been identified as potentially responsible for therapeutic effects. The information available on V. crocata is predominantly empirical. The few scientific reports on its biological activity have confirmed the efficacy of the plant as a wound healing agent, antidiabetic, and diuretic. It is necessary to properly characterize the active principles and carry out evaluations of their mechanisms of action and toxicity.

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  • García-Alvarado JS, Verde-Star MJ, Heredia NL. Traditional uses and scientific knowledge of medicinal plants from Mexico and Central America. J Herbs Spices Med Plants. 2001; 8(2-3): 37–89.
  • Martínez-Moreno D, Reyes-Matamoros J, Andrés-Hernández AR, Pérez-Espinosa L. Flora útil de la comunidad “Rancho El Salado” en Jolalpan, México [Useful flora of the “Rancho El Salado” community in Jolalpan, Mexico]. Rev Iberoam Cienc. 2016; 3(4): 1–15.
  • Ortega-Cala LL, Monroy-Ortiz C, Monroy-Martínez R, Colín-Bahena H, Flores-Franco G, Luna-Cavazos M, Monroy-Ortiz R. Medicinal plants used for diseases of the digestive system in Tetela del Volcan, State of Morelos, Bol Latinoam Caribe Plantas Med Aromat. 2019; 18(2): 106–129.
  • Vibrans H. Malezas de México [Weeds of Mexico], Verbesina crocata (Cav.) Less. Comisión Nacional Para El Conocimiento y Uso De La Biodiversidad, México. [National Commission for the Knowledge and Use of Biodiversity, Mexico]. [Accessed 2022 August 15]. Available from: http://www.conabio.gob.mx/malezasdemexico/asteraceae/verbesina-crocata/fichas/ficha.htm.
  • Velasco-Ramírez AP, Velasco-Ramírez SF, Velasco-Ramírez A. Use in traditional medicine of Verbesina sphaerocephala Gray (Asteraceae) in the community of San Martin de las Flores, Jalisco, Mexico. Bol Latinoam Caribe Plantas Med Aromat. 2019; 18(2): 144–154.
  • García-Bores AM, Álvarez-Santos N, López-Villafranco ME, Jácquez-Ríos MP, Aguilar-Rodríguez S, Grego-Valencia D, Espinosa-González AM, Estrella-Parra EA, Hernández-Delgado CT, Serrano-Parrales R, González-Valle MR, Benítez-Flores JC. Verbesina crocata: a pharmacognostic study for the treatment of wound healing. Saudi J Biol Sci. 2020; 27(11): 3113–3124.
  • Monroy R, Ayala I. Importancia del conocimiento etnobotánico frente al proceso de urbanización. [Importance of ethnobotanical knowledge in the face of the urbanization process]. Etnobiología. 2003; 3(1): 79–92.
  • Canales M, Hernández T, Caballero J, Romo De Vivar A, Avila G, Duran A, Lira R. Informant consensus factor and antibacterial activity of the medicinal plants used by the people of San Rafael Coxcatlán, Puebla, México. J Ethnopharmacol. 2005; 97(3): 429–439.
  • Salazar-Gómez A, Pablo-Pérez SS, Estévez-Carmona MM, Meléndez-Camargo ME. Diuretic activity of aqueous extract and smoothie preparation of Verbesina crocata in rat. Bangladesh J Pharmacol. 2018; 13(3): 236–240.
  • Barragán-Solís A. The practice of self-care by phytotherapy in a group of Mexican families. Arch Med Fam. 2006; 8(3): 150–162.
  • Waizel-Bucay J, Waizel-Haiat S. Antitussive plants used in Mexican traditional medicine. Pharmacogn Rev. 2009; 3(5): 22–36.
  • Arenas FS. Etnobotánica y usos potenciales del Cirián (Crescentia alata, HBK) en el estado de Morelos. [Ethnobotany and potential uses of Cirián (Crescentia alata, HBK) in the state of Morelos]. Polibotánica. 2004; 18: 13–31.
  • Pérez RM, Ocegueda ZA, Muñoz JL, Avila JG, Morrow WW. A study of the hypoglucemic effect of some Mexican plants. J Ethnopharmacol. 1984; 12(3): 253–262.
  • Marles RJ, Farnsworth NR. Antidiabetic plants and their active constituents. Phytomedicine. 1995; 2(2): 137–189.
  • Gu Y, Yang X, Shang C, Thao TTP, Koyama T. Inhibitory properties of saponin from Eleocharis dulcis peel against α-glucosidase. RSC Adv. 2021; 11(25): 15400–15409.
  • Gupta R, Sharma AK, Sharma MC, Dobhal MP, Gupta RS. Evaluation of antidiabetic and antioxidant potential of lupeol in experimental hyperglycaemia. Nat Prod Res. 2021; 26(12): 1125–1129.
  • Fred-Jaiyesimi AA, Ibukunoluwa BB. Lupeol acetate from Macaranga barteri Müll-Arg leaf lowers blood glucose level in alloxan induced diabetic rats. Nig Q J Hosp Med. 2016; 26(1): 368–371.
  • Neef H, Declercq P, Laekeman G. Hypoglycaemic activity of selected European plants. Phytother Res. 1995; 9(1): 45–48.

Oelrichs PB, Vallely PJ, MacLeod JK, Lewis IAS. Isolation of galegine from Verbesina enceloiodes. J Nat Prod. 1981; 44(6): 754–755.