Document Type : Original paper
Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Department of Pharmacognosy and Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.
Medicinal Plants Research Center, Institute of Medicinal Plants, ACECR, Karaj, Iran.
Department of Pharmacognosy, School of Pharmacy, International Campus, Tehran University of Medical Sciences, Tehran, Iran.
Background and objectives: The oleo-gum resin from Ferula gummosa Bioss. is commercially important. Variability of geographic location has shown a deep effect on essential oil of different genus of plants. Thus, evaluation of oleo-gum resin of Ferula gummosa from different locations is important for further studies. In the present study, phytochemicals profile of essential oil of oleo-gum resins from F. gummosa in different geographic location and various bioclimates of Iran, were studied. Methods: The oleo-gum resin of F. gummosa was collected from different regions of Iran. The essential oils of the samples were extracted by Clevenger apparatus and were analyzed by GC-MS. Results: The highest amount of essential oil compared was observed in the samples from Damghan area (24.0%), Firuzkuh area (22%) and Kalat-e-Naderi area (22%). The variability in the oil composition of different samples exhibited a notable difference in monoterpenes content from 39.15 % to 87.48%. Based on GC-MS analysis, the major components were β-pinene (5.11-63.80 %), sabinene (3.37-30.69%), α-pinene (4.43-12.72%) and δ-carene (2.38-10.23 %). The highest concentrations of β-pinene (63.80%) and sabinene (30.69%) were observed in the Shiraz and Torbat-e-Jam essential oils, respectively. The highest amounts of α-pinene (12.72%) and δ-carene (10.23%) were recorded in Firuzkuh and Shiraz areas, respectively. Conclusion: Significant variation in the component of the essential oils from different oleo-gum resins can be used to improve the knowledge about the endemic medicinal plants.