Chemical Composition and Biological Effects of Pistacia atlantica Desf. Oleoresin Essential Oil

Document Type : Original paper

Authors

1 Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

2 Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

3 Persian Medicine and Pharmacy Research Center, Tehran University of Medical Sciences, Tehran, Iran.

4 Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC, Canada.

5 Department of Pharmaceutical Biotechnology, Faculty of Pharmacy and Biotechnology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

6 Shahid BeDepartment of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences,Tehran, Iran.heshti University of Medical Sciences,

Abstract

Background and objectives: The oleoresin of Pistacia atlantica Desf. (known as “Baneh” in Iran) has been frequently used in traditional medicine for its medicinal properties. Herein, P. atlantica essential oil was investigated for its antimicrobial and α-glucosidase inhibitory activities since α-pinene which has been identified as the most abundant component in Pistacia genus oil, has demonstrated antimicrobial and anti-α-glucosidase properties. Methods: Fresh oleoresin was collected from Javanroud, Kermanshah, Iran and the essential oil was obtained by Clevenger-type apparatus. The chemical composition of essential oil was identified with GC/MS analysis and compared with those reported from various regions. The antimicrobial activity was evaluated against various strains (Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Candida albicans, Saccharomyces cerevisiae, and Lactobacilli spp.) through MIC method. Also, its anti-α-glucosidase property and antioxidant activity by DPPH assay were investigated. Results: GC/MS analysis of the essential oil confirmed the presence of nineteen compounds and among them, α-pinene (64.8%) was identified as the major constituent. Also, β-pinene (5.7%) and cis-limonene oxide (4.5%) were relatively abundant. Our results revealed antimicrobial properties of the “Baneh” essential oil against various bacterial and fungal strains. Moreover, it demonstrated inhibitory activity toward α-glucosidase with IC50 value of 41.5 ± 2.5 mg/mL compared with acarbose (IC50=0.5±0.2 mg/mL). DPPH free-radical scavenging activity assay showed antioxidant activity with IC50 value of 155.2 ± 1.4 mg/mL compared with quercetin (IC50=250.0±0.0 μg/mL). Conclusion: Pistacia atlantica oleoresin essential oil depicted satisfactory antimicrobial activity against both Gram-positive and Gram-negative strains. However, it demonstrated low antioxidant and α-glucosidase inhibitory effects.

Keywords

Main Subjects

References

  • Pourreza M, Shaw JD, Zangeneh H. Sustainability of wild pistachio (Pistacia atlantica ) in Zagros forests. For Ecol Manage. 2008; 255(11): 3667–3671.
  • Ahmed ZB, Yousfi M, Viaene J, Dejaegher B, Demeyer K, Heyden YV. Four Pistacia atlantica subspecies (atlantica, cabulica, kurdica and mutica): a review of their botany, ethnobotany, phytochemistry and pharmacology. J Ethnopharmacol. 2021; Article ID 113329.
  • Kasabri V, Afifi FU, Hamdan I. In vitro and in vivo acute antihyperglycemic effects of five selected indigenous plants from Jordan used in traditional medicine. J Ethnopharmacol. 2011; 133(2): 888–896.
  • Ahmed ZB, Yousfi M, Viaene J, Dejaegher B, Demeyer K, Mangelings D, Vander Heyden Y. Potentially antidiabetic and antihypertensive compounds identified from Pistacia atlantica leaf extracts by LC fingerprinting. J Pharm Biomed Anal. 2018; 5(149): 547–556.
  • Hashemnia M, Nikousefat Z, Yazdani-Rostam M. Antidiabetic effect of Pistacia atlantica and Amygdalus scoparia in streptozotocin-induced diabetic mice. Comp Clin Pathol. 2015; 24(6): 1301–1306.
  • Panikar S, Shoba G, Arun M, Sahayarayan JJ, Usha Raja Nanthini A, Chinnathambi A, Alharbi SA, Nasif O, Kim HJ. Essential oils as an effective alternative for the treatment of COVID-19: molecular interaction analysis of protease (Mpro) with pharmacokinetics and toxicological properties. J Infect Public Health. 2021; 14(5): 601–610.
  • Ayub M, Hanif M, Sarfraz R, Muhammad Shahid M. Biological activity of Boswellia serrate oleo gum resin essential oil: effects of extraction by supercritical carbon dioxide and traditional methods. Int J Food Prop. 2018; 21(1): 808–820.
  • Memariani Z, Sharifzadeh M, Bozorgi M, Hajimahmoodi M, Farzaei MH, Gholami M, Siavoshi F, Saniee P. Protective effect of essential oil of Pistacia atlantica on peptic ulcer: role of α-pinene. J Tradit Chin Med. 2017; 37(1): 57–63.
  • Labdelli A, Zemour K, Simon V, Cerny M, Adda A, Merah O. Pistacia atlantica, a source of healthy vegetable oil. Appl Sci. 2019; 9(12): 1–11.
  • Ghalem BR, Mohamed M. Essential oil from gum of Pistacia atlantica Desf: screening of antimicrobial activity. Afr J Pharm Pharmacol. 2009; 3(1): 13–15.
  • Benabderrahmane M, Benali M, Aouissat H, Jordán MJ. Antimicrobial activity of the essential oils of Pistacia atlantica from Algeria. 2009; 7(6): 304–308.
  • Biswas S, Koul M, Bhatnagar AK. Effect of salt, drought and metal stress on essential oil yield and quality in plants. Nat Prod Commun. 2011; 6(10): 1559–1564.
  • Locali-Pereira AR, Lopes NA, Menis-Henrique MEC, Janzantti NS, Nicoletti VR. Modulation of volatile release and antimicrobial properties of pink pepper essential oil by microencapsulation in single- and double-layer structured matrices. Int J Food Microbiol. 2020; Article ID 108890.
  • Asadollahzadeh H, Shamspur T. Chemical composition of the extracts of fruits of Pistacia atlantica from Kerman province in Iran. J Essent Oil-Bear Plants. 2013; 16(2): 243–246.
  • Adams RP. Identification of essential oil components by gas chromatography mass spectrometry. 4th Carol Stream: Allured Publishing, 2007.
  • Kiashi F, Hadjiakhoondi A, Tofighi Z, Khanavi M, Ajani Y, Ahmadi Koulaei S, Yassa N. Compositions of essential oils and some biological properties of Stachys laxa & Buhse and S. byzantina K. Koch. Res J Pharmacogn. 2021; 8(2): 5–15.
  • Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: a review. J Pharm Analysis. 2016; 6(2): 71–79
  • Saeedi M, Raeisi-Nafchi M, Sobhani S, Mirfazli SS, Zardkanlou M, Mojtabavi S, Faramarzi MA, Akbarzadeh T. Synthesis of 4-alkylaminoimidazo[1,2-a] pyridines linked to carbamate moiety as potent α-glucosidase inhibitors. Mol Divers. 2021; 25(4): 2399–2409.
  • Klesk K, Qian M. Preliminary aroma comparison of marion (Rubus hyb) and evergreen (R. laciniatus L.) blackberries by dynamic headspace/OSME technique. J Food Sci. 2003; 68(2): 697–700.
  • Bylaite E, Meyer AS. Characterisation of volatile aroma compounds of orange juices by three dynamic and static headspace gas chromatography techniques. Eur Food Res Technol. 2006; 222(1): 176–184.
  • Miyazaki T, Plotto A, Goodner K, Gmitter FG. Distribution of aroma volatile compounds in tangerine hybrids and proposed inheritance. J Sci Food Agric. 2011; 91(3): 449–460.
  • Kim TH, Thuy NT, Shin JH, Baek HH, Lee HJ. Aroma-active compounds of miniature beefsteak plant (Mosla dianthera). J Agric Food Chem. 2000; 48(7): 2877–2881.
  • Adams RP, González Elizondo MS, González Elizondo M, Slinkman E. DNA fingerprinting and terpenoid analysis of Juniperus blancoi var. huehuentensis (Cupressaceae), a new subalpine variety from Durango, Mexico. Biochem Syst Ecol. 2006; 34(3): 205–211.
  • Baccouri B, Ben Temime S, Campeol E, Cioni PL, Daoud D, Zarrouk M. Application of solid-phase microextraction to the analysis of volatile compounds in virgin olive oils from five new cultivars. Food Chem. 2007; 102(3): 850–856.
  • Loayza I, Abujder D, Aranda R, Jakupovic J, Collin G, Deslauriers H, Jean FI. Essential oils of Baccharis salicifolia, latifolia and B. dracunculifolia. Phytochemistry. 1995; 38(2): 381–389.
  • Senatore F, Napolitano F, Arnold NA, Bruno M, Herz W. Composition and antimicrobial activity of the essential oil of Achillea falcata (Asteraceae). Flavour Fragr J. 2005; 20(3): 291–294.
  • Choi HS. Character impact odorants of Citrus Hallabong [( unshiu Marcov × C. sinensis Osbeck) × C. reticulata Blanco] cold-pressed peel oil. J Agric Food Chem. 2003; 51(9): 2687–2692.
  • Courtois EA, Paine CE, Blandinieres PA, Stien D, Bessiere JM, Houel E, Baraloto C, Chave J. Diversity of the volatile organic compounds emitted by 55 species of tropical trees: a survey in French Guiana. J Chem Ecol. 2009; 35(11): 1349–1362.
  • Kowalski R, Wolski T. The chemical composition of essential oils of Silphium perfoliatum Flavour Fragr J. 2005; 20(3): 306–310.
  • Goodner KL, Mahattanatawee K, Plotto A, Sotomayor JA, Jordan MJ. Aromatic profiles of Thymus hyemalis and Spanish vulgaris essential oils by GC-MS/GC-O. Ind Crops Prod. 2006; 24(3): 264–268.
  • Hamm S, Bleton J, Connan J, Tchapla A. A chemical investigation by headspace SPME and GC-MS of volatile and semi-volatile terpenes in various olibanum samples. Phytochemistry. 2005; 66(12): 1499–1514.
  • Mitiku SB, Sawamura M, Itoh T, Ukeda H. Volatile components of peel cold-pressed oils of two cultivars of sweet orange (Citrus sinensis (L.) Osbeck) from Ethiopia. Flavour Fragr J. 2000; 15(4): 240–244.
  • Lawal OA, Oyedelji AO. Chemical composition of the essential oils of Cyperus rotundus from South Africa. Molecules. 2009; 14(8): 2909–2917.
  • Mosayebi M, Amin G, Arzani H, Azarnivand H, Maleki M, Shafaghat A. Effect of habitat on essential oil of Achillea filipendula in Iran. Asian J Plant Sci. 2008; 7(8): 779–781.
  • Didehvar M, Ebadi M, Ayyari M. Qualitative and quantitative evaluation of Pistacia atlantica essential oil from thirteen ‎natural habitats. Iran J Hortic Sci. 2021; 52(2): 419–428.
  • Izadyar S, Babaei Y, Efhamisisi D. Effect of natural resin from wild pistachio trees on physical properties and durability of beech wood: alone and in combination with boric acid. Drvna Ind. 2020; 71(4): 379–388.
  • Peivastegan M, Rajabi M, Zaferani Arani H, Olya M, Atashi HA, Abolghasemi SH. Comparing the effects of oleoresin of Pistacia atlantica tree and diclofenac gel on the knee osteoarthritis improvement. Shiraz E-Med J. 2020; 21(10): 1–8.
  • Savedoroudi P, Mirzajani F, Aliahmadi A, Ghassempour A. Top-down thermal analysis versus bottom-up gas chromatography–mass spectrometry in an adulteration study of Pistacia atlantica oleoresin. J Therm Anal Calorim. 2016; 123: 2451–2457.
  • Najafi MBH, Farimani RH, Tavakoli J, Madayeni S. GC-MS analysis and antimicrobial activity of the essential oil of trunk exudates of Pistacia atlantica mutica. Chem Nat Compd. 2014; 50(2): 376–378.
  • Hosseini F, Adlgostar A, Sharifnia F. Antibacterial activity of Pistacia atlantica extracts on Streptococcus mutans Int Res J Biological Sci. 2013; 2(2): 1–7.
  • Sharifi MS, Hazell SL. GC-MS analysis and antimicrobial activity of the essential oil of the trunk exudates from Pistacia atlantica kurdica. J Pharm Sci Res. 2011; 3(8): 1364–1367.
  • Delazar A, Reid RG, Sarker SD. GC-MS analysis of the essential oil from the oleoresin of Pistacia atlantica mutica. Chem Nat Compd. 2004; 40(1): 24–27.
  • Benhassaini H, Bendeddouche FZ, Mehdadi Z, Romane A. GC/MS analysis of the essential oil from the oleoresin of Pistacia atlantica subsp. atlantica from Algeria. Nat Prod Commun. 2008. 3(6): 929–932.
  • Benabderrahmane M, Aouissat M, Bueso MJ, Bouzidi A, Benali M. Chemical composition of essential oils from the oleoresin of Pistacia atlantica from Algeria. J Biochem Int. 2015; 2(4): 133–137.
  • Awla Shekhany H, Ahemad H. The study of chemical composition of gum in Pistacia atlantica in Erbil region. Zanco J Pure Appl Sci. 2018; 30(3): 26–32.
  • Barrero AF, Herrador MM, Arteaga JF, Akssira M, Mellouki F, Belgarrabe A, Blázquez MA. Chemical composition of the essential oils of Pistacia atlantica J Essent Oil Res. 2005; 17(1): 52–54.
  • Aksoy A, Duran N, Koksal F. In vitro and in vivo antimicrobial effects of mastic chewing gum against Streptococcus mutans and mutans streptococci. Arch Oral Biol. 2006; 51(6): 476–481.
  • Daifas DP, Smith JP, Blanchfield B, Sanders G, Austin JW, Koukoutisis J. Effects of mastic resin and its essential oil on the growth of proteolytic Clostridium botulinum. Int J Food Microbiol. 2004; 94(3): 313–322.
  • Leite AM, Lima EO, Souza EL, Melo Diniz MFF, Trajano VN, Medeiros IA. Inhibitory effect of beta-pinene, alpha-pinene and eugenol on the growth of potential infectious endocarditis causing Gram-positive bacteria. Rev Bras Cienc Farm. 2007; 43(1): 121–126.
  • Moreira ACP, Lima EO, Souza EL, Dingenen MAV, Trajano VN. Inhibitory effect of Cinnamomum zeylanicum Blume (Lauraceae) essential oil and β-pinene on the growth of dematiaceous moulds. Braz J Microbiol. 2007; 38(1): 33–38.
  • Lima IO, Oiviera RAG, Lima EO, Souza EL, Farias NP, Navarro DF. Inhibitory action of some phytochemicals on yeasts potentially causing of opportunistic infections. Rev Bras Cienc Farm. 2005; 41(2): 199–203.
  • Salehi B, Upadhyay S, Orhan IE, Jugran AK, Jayaweera SLD, Dias DA, Sharopov F, Taheri Y, Martins N, Baghalpour N, Cho WC, Sharifi-Rad J. Therapeutic potential of α- and β-pinene: a miracle gift of nature. Biomolecules. 2019; 9(11): 1–34.
  • Ben Arfa A, Combes S, Preziosi-Belloy L, Gontard N, Chalier P. Antimicrobial activity of carvacrol related to its chemical structure. Lett Appl Microbiol. 2006; 43(2): 149–154.
  • Moumni S, Elaissi A, Trabelsi A, Merghni A, Chraief I, Jelassi B, Chemi R, Ferchichi S. Correlation between chemical composition and antibacterial activity of some Lamiaceae species essential oils from Tunisia. BMC Complement Med Ther. 2020; 20(1): 1–15.
  • Miladinović DL, Dimitrijević MV, Mihajilov-Krstev TM, Marković MS, Ćirić VM. The significance of minor components on the antibacterial activity of essential oil via chemometrics. LWT. 2021; Article ID 110305.
  • Wu T, Luo J, Xu B. In vitro antidiabetic effects of selected fruits and vegetables against glycosidase and aldose reductase. Food Sci Nutr. 2015; 3(6): 495–505.
  • Toyomizu M, Sugiyama S, Jin R, Nakatsu T. α‐Glucosidase and aldose reductase inhibitors: constituents of cashew, Anacardium occidentale, nut shell liquids. Phytother Res. 1993; 7(3): 252–254.
  • Shihabudeen HMS, Priscilla DH, Thirumurugan K. Cinnamon extract inhibited the α‐glucosidase activity and dampens postprandial glucose excursion in diabetic rats. Nutr Metab. 2011; 8(1): 1–11.
  • Jaradat NA, Al-Maharik N, Abdallah S, Shawahna R, Mosa A, Qtishat A. Nepeta curviflora essential oil: phytochemical composition, antioxidant, anti-proliferative and anti-migratory efficacy against cervical cancer cells, and α-glucosidase, α-amylase and porcine pancreatic lipase inhibitory activities. Ind Crops Prod. 2020; 158: 1–11.
  • Oboh G, Olasehinde TA, Ademosun AO. Inhibition of enzymes linked to type-2 diabetes and hypertension by essential oils from peels of orange and lemon. Int J Food Prop. 2017; 20(S1(: 586–
  • Majouli K, Hlila MB, Hamdi A, Flamini G, Jannet HB, Kenani A. Antioxidant activity and α-glucosidase inhibition by essential oils from Hertia cheirifolia (L.). Ind Crops Prod. 2015; 82: 23–28.

 

Research Journal of Pharmacognosy
Volume 9, Issue 3
July 2022
Pages 25-33

Files

Share

How to cite

Statistics