A Comprehensive Review about Quercus infectoria G. Olivier Gall

Document Type: Review


1 Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

2 Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

3 Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Department of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

4 Department of Traditional Medicine, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Department of Natural Resources and Water Management, Khorramabad, Iran.

6 Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

7 Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Phytopharmaceutical Technology and Traditional Medicine Incubator, Shiraz University of Medical Sciences, Shiraz, Iran.



Due to an interaction between gall wasp Andricus sternlichti Bellido and Quercus infectoria G.Olivier from Fagaceae, the oak galls with a wide range of industrial and pharmaceutical applications are produced. Quercus infectoria galls have been well-known by both ethnopharmacology and traditional medicine of Iran. The aim of current study was a comprehensive collection of Persian scholars' notions and recent findings about medicinal effects of this gall. Sixteen traditional manuscripts of one millennium were sought by two keywords (“Afs” and “Mazu”. Arabic and Persian names of Quercus gall, respectively), and relevant articles till October 2018 were reviewed. In traditional manuscripts, three main dosage forms from gall including decoction, powder, and poultice were found. They had been prescribed for about of thirty disorders. Except for one clinical trial, other articles described related to animal studies and antimicrobial effect evaluation. Since Quercus infectoria gall as an endemic natural product of Iran is a valuable source for export, ethnic usages and pharmaceutical applications, the outcomes of this study can be beneficial for researchers involved in development of natural medications.


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